Math 151 , Fall 2008 Wed. Day 23, Oct. 22Hit reload.....after class.

HW:  Read Chapter 9, first to p. 224.  Check p. 228: 9.16, 17, 18, 20 (obs/expt, factors:: then 21 (choosing groups), then read p. 224 on, then Check 9.19, 22, 23, 25. Read Data Ethics, pp. 235-242.

Hand in  next time:
A. Google Bradley effect  and "spiral of silence."
1) What phenomena do they describe?
2) How is this relevant to presidential polling right now?
Ch. 9

p. 229 9.27 wine, beer, spirits , diagram design.
p. 230 9.32 a only headache prevention design
p. 231 9.33 fabric finishing, design

p. 230, 9.28 marijuana Use the Simple Random Sample Applet, see below for details, to find who to put in the two groups.  Also: pick just the first 3 people for the "weak" group using Table B at line 131.
p230, 9.30 TV ads  Use the Simple Random Sample Applet, see below for details.

p. 234, 9.48 Randomization avoids bias
p. 222, 9.8 conserving energy
p. 223, 9.9 exercise/heart
p. 233, 9.45 a,b,c,e antioxidants (review) 

DO p. 243 #7 anonymity or confidentiality? (read pp. 237-8)
- - - - - - - - - - 
p. 233, 9.45 d antioxidants, significance (review) 
 
p. 222 9.10 significance on Monday
- -- - .Postpone Other designs.
p. 226, 9.13 hand strength, MP
p. 231, 9.35 forest CO2 , CR/MP

p. 226, 9.15 teaching techn.  Why might I call this a  matched pairs rather than a general block design?   Don't actually do the randomization, but think about what ought to be done; we'll talk about it.
p. 232, 9.40 TV ads, block design.  Use the  Applet, to assign your subjects.  Number your Women and your Men, and show their numbers as well as the group they're in. 
p. 229, 232, 9.27 and 9.39 wine, beer, spirits two ways

+ + + + + + + + + +
Hand in Monday
Separate paper:
Hand in answers to these questions on the "Placebo Effect" articles (outside my door/on reserve): 
a) Give two examples of the placebo effect (from the article!)
b) What do researchers believe causes the placebo effect? 
c)  In the separate article: "Pill will make you feel better...," what country was surveyed?

Read, to discuss 

p. 233, 9.43 quick randomizing 

p. 234, 9.47 explaining medical research

p.233 9.41 prayer & meditation (clarification: they help the person praying; careful experiments to see if they help a person prayed for have not shown positive results.)

.Postpone .
p. 232, 9.38  spine fractures block design. You lack the information to make a complete design (i.e. how many women at each hospital.)  Sketch in what you can.
Optional
 

  Think about this one...
p. 230, 9.29 red wine. 
This is a complex experiment with different amounts of polyphenols in different kinds of liquids.
 Doesn't fall neatly into our Factors-value structures?
 Think about it a bit...


.Postpone .
p. 226, 9.14 matched and not, more practice
 

News: (& graphic)  The American dream: anyone can become president, anyone can get rich. (?)
"Gap between rich and poor has grown in more than three-quarters of OECD countries over the past two decades"OECD_rich_poor
OECD’s Growing Unequal? www.oecd.org/els/social/inequality   (OECD--30 developed countries:  representative gov't, free market economy)
Graph (Finfacts) With mean income of lowest 10% as base, what is the multiple of that for the mean(?) of the highest 10%?  Note US, 3rd worst after Mexico and Turkey.

"Countries with a wide distribution of income tend to have more widespread income poverty. Also, social mobility is lower in countries with high inequality, such as Italy, the United Kingdom and the United States, and higher in the Nordic countries where income is distributed more evenly.

In most OECD countries, around half of poor people are better off and move above the poverty line within three years. This figure is the highest in Denmark and the Netherlands. Income mobility means that people who are persistently poor make up less than 2% of the population in these two countries. But persistent poverty is much more widespread – 7% of the population – in Australia, Greece, Ireland, Portugal and the United States.   (Finfacts)  http://www.finfacts.ie/irishfinancenews/article_1015037.shtml


"In the United States, the richest 10 percent earn an average of $93,000 -- the highest level in the OECD. The poorest 10 percent earn an average of $5,800 -- about 20 percent lower than the OECD average."  (Business Week)  http://www.businessweek.com/ap/financialnews/D93UU9980.htm

Since the mid 1980s France, Greece and Spain were some of the few countries where income gaps shrank, the Paris-based organization said. Over the past five years, income inequality and poverty increased the most in the U.S., Canada, Germany and Norway, while the gap shrank in Greece, Mexico and the U.K.  (Bloomberg) gapminder graph
http://www.gapminder.org/ Amazing graph tool, with lots of data

HW Questions?  Day 22


Ch. 9 Designing Experiments

Review+new: Summary.   Details Day 22
    
     Observational Study   vs. Experiment
  day 20
                Different jargon; different traditions.
Do something to:
  "Experimental Units" = "Subjects" = individuals.
Treatment:  Specific experimental condition we impose on one or more subjects.
Factor: Explanatory Variable we manipulate. We set specific Values (levels)
Response variable(s)  Results that we measure.

E.g. 2 headache medications, in combination?
A two-factor experiment, each with 3 values (levels). 9 possible treatments.
    Factor A: Aspirin: values: None, 500 mg, 1000 mg
    Factor B: Caffeine: values: None, 50 mg, 100 mg
Response variable: reported pain relief

 Lurking variables:  Control--how?  Nothing except experimental treatment should differentially affect response.
    Compare responses under several treatments, look at differences.
Placebo effect: a positive response to a "sham" medical treatment
"Control group" Group that gets the "baseline"--"null"-- "none" or "placebo" value of the factor. 
 Always: trying to make everything "the same" except for our treatments, to try to eliminate confounding/lurking variable effects.

.New today.
How to get groups "just like" one another?  Randomize who goes into which group.  (Usually our batch of  experimental units is not a random sample from the population of all individuals--volunteers, etc.)
Randomized comparative experiment : Diagrams of design, Moore pp. 218-19: shows where randomizing happens, how many to each treatment, what the treatments are.
Completely randomized: all exp. units allocated at random among the treatments. Applet or random # table.

Use enough subjects for each treatment so that you can  "average out" (and measure) chance variation in the subjects. 

Principles of designing an experiment (p. 221) See above:

More problems, cautions:
Placebo and biasing effects can result from expectations.   "Blind", "Double blind"

Did you forget to measure something that might be a lurking variable??  Measure everything you can...

Lack of realism:  
Do sociology, psychology experiments generalize to "real life?"
--Subjects are not a random sample from the population. (Most psychology "facts" were based on studies of Ivy League males, before 1970's.)
--Ethical questions...Milgram.  Whole section BPS4e, pp. 235-242

New material:
Statistical Significance p.221: An observed effect so large that it would rarely occur by chance (assuming no real difference in treatments) is called "statistically significant".   "So large", "rarely", "by chance" will be defined and quantified in Ch. 6.
Example:  Suppose 95% of the subjects  had their headaches cured by treatment 9 and only 25%  by treatment 1 (placebo).  IF the medicine in fact did "no good" that would be a very unlikely outcome (at least if we have "enough" people in each treatment).  So we will say the difference in headache cures between treatment 1 and treatment 9 is "statistically significant" and be inclined to believe the medicine "works".
Example: Gallup says Obama "significantly" ahead: difference they got is so large that they would rarely see such a difference in a sample if indeed the two candidates had the same support.
(What's "rarely"? They do samples all the time. Rarely = 1 in 20? 1 in 100?   1 in 20 is common usage, 1 in 100 also...)
= = = = =.Start here Friday. = = = = = = =
Fancier Experimental designs (not "completely randomized") Control extraneous variability by pre-sorting individuals into  homogeneous "blocks".  Do usual design on each block. (BPS4e pp. 224-226)
Matched pairs: To compare Control and experimental treatments (i.e. 2 values only)
   Sort experimental units into "matching" pairs.   One member of pair gets control, other gets experimental.
                Randomize which.
        Compare within pair, then summarize all comparisons.
  Common: Do the control and experiment to same individual (matched with self = "self-paired"). (Randomize order)
        Are right feet bigger than left feet? (not an experiment)      Sunburn salve experiment?
    Aside:  Sampling data, "longitudinal study" following same people through time.
            Works like matched pair to control variability.
Block design:  Sort experimental units into "Blocks" = groups homogeneous on potentially confounding variables
     e.g. M/F, age, income, weight, fruitflies wild or curly-winged.  (No randomization here yet.)
    Within each block, randomize the treatments. Compare results  within each block, then summarize all results.
    (Matched pairs is a special case of block design--each pair is a tiny "block".)  Diagram p. 226


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